01
Best overall pick
The Original Pizza Place
Downtown Marietta • Classic Ohio Valley Pizzeria • Local Favorite
A river-town institution turning out crisp, square-cut pies that keep Marietta college kids and road-trippers coming back.
This long-running shop specializes in the kind of thin, airy crust and edge-to-edge cheese that define Ohio Valley-style pizza. Slices are quick, cheap, and just greasy enough in the best way, making it an easy stop before or after a walk along the Muskingum. Go simple with pepperoni, or grab a couple of different slices to sample their rotating specialty toppings.
02
Worth-the-drive classic
Jukebox Pizza
Waterford Countryside • Small-Town Pizza Parlor • Best For Hearty Portions
A destination pie shop where big, loaded pizzas and a laid-back country vibe make the drive from Antioch feel like part of the treat.
Jukebox leans into the old-school, small-town feel: generous toppings, thick cheese, and a crust sturdy enough to hold it all. It is the kind of place where families linger over a large combo pie and leftovers are expected. If you like a substantial, saucy pizza and do not mind a bit of a scenic drive through Washington County, this one belongs on your list.
03
Most reliable late-night option
Domino's Pizza
Marietta Commercial Strip • Chain Delivery And Carryout Shop • Best For Late-Night Delivery
A dependable go-to for hot, customizable pizza when you are back from the river or a ballgame and everything else is closed.
While it is a national chain, the Marietta Domino's is a practical choice for Antioch folks who want consistent pizza without fuss. The menu covers hand-tossed, pan, and thin-crust options, plus wings and pasta for mixed groups. Online ordering and tracking make it easy to time a pickup on your way home or line up a delivery to your lodging in town.
04
Ohio Valley classic
DeFelice Bros. Pizza
St. Clairsville Shopping Corridor • Regional Pizza Chain Eatery • Best For Classic Toppings
A beloved Ohio Valley chain known for its chewy crust, well-seasoned sauce, and generous piles of traditional toppings.
DeFelice Bros. has deep roots in the Ohio River valley, and the St. Clairsville location carries that tradition with a crowd-pleasing menu. Expect a slightly thicker crust, lots of cheese, and toppings that go right out to the edge. It is an easy add-on to a day of errands around the mall or a road trip up the river from Monroe County.
05
Family-friendly sit-down spot
Giovanni's Pizza
Caldwell Town Center • Casual Italian-Style Pizzeria • Best For Families
A relaxed small-town restaurant where you can pair crowd-pleasing pizzas with salads and baked pasta without rushing the meal.
Giovanni's is a regional chain that feels more like a neighborhood Italian spot, and the Caldwell location is especially welcoming to families. Alongside their pan and traditional crust pizzas, you will find calzones, pasta bakes, and plenty of shareable sides. It is a nice choice when you want to sit down, let the kids spread out a bit, and make a full evening out of pizza night away from home.