01
Classic Ohio Valley pick
Di Carlo's Pizza – St. Clairsville
St. Clairsville Shopping Strip • Ohio Valley Square-Cut Pizzeria • Classic Hometown Slice
A go-to for those signature square-cut pans with sauce-first, cheese-later Ohio Valley style.
If you want the style of pizza the Ohio Valley is famous for, this St. Clairsville Di Carlo’s is the closest sure bet from Glencoe. Expect airy crust, tangy sauce, and that distinctive layer of cheese added after the bake. It is a simple counter-service spot, ideal for grabbing a box to take back home or to a nearby park.
02
Best for loaded specialty pies
DeFelice Brothers Pizza – St. Clairsville
Just Off I-70 In St. Clairsville • Family-Run Regional Pizza Shop • Best For Customizable Pies
Thick with toppings, with plenty of specialty pizzas and subs to cover a full family meal.
DeFelice Brothers brings a slightly heartier take on Ohio Valley pizza, with a soft, bready crust and generous toppings. From works-style pies to classic pepperoni and sausage, most combinations land well with both locals and travelers off the interstate. It is an easy option when you are feeding a crowd and want something reliable close to the highway.
03
Best for dine-in with friends
Pizza Milano – St. Clairsville
Central St. Clairsville • Casual Italian Pizza Joint • Best For Big Groups
A sit-down spot with big, shareable pies, stromboli, and plenty of red-sauce comfort food.
Pizza Milano feels like the classic small-town Italian place where everyone ends up after games and family events. The pizzas run large, with a straightforward crust and plenty of cheese, and the menu backs it up with pasta, sandwiches, and wings. It is a good choice when you want to linger over a meal instead of just grabbing a quick box to go.
04
Delivery workhorse
Domino's Pizza – St. Clairsville
St. Clairsville Residential Corridor • National Delivery-Focused Chain • Late-Night And Delivery Pick
Fast, predictable delivery with all the familiar crusts, sauces, and coupon-friendly combos.
When convenience matters more than anything, the St. Clairsville Domino’s is the easiest way to get pizza out to Glencoe and the surrounding back roads. The menu hits all the chain standards, from hand-tossed and pan pizzas to stuffed cheesy bread and wings. It is particularly handy for late evenings, game nights, or when you need to feed a group without leaving home.
05
Worth-the-drive riverfront stop
Di Carlo's Pizza – Bellaire
Downtown Bellaire By The River • Old-School Ohio Valley Pizza Shop • Destination Slice Outing
A no-frills Bellaire storefront turning out nostalgic square-cut trays that locals swear by.
If you do not mind a slightly longer drive from Glencoe, the Bellaire Di Carlo’s gives you that same iconic style in a more old-school, river-town setting. The menu is focused, the space is bare-bones, and the emphasis is squarely on hot pans and quick service. It is the kind of place where grabbing a few trays and eating them in the car or at a nearby picnic table feels perfectly right.