01
Best overall pick
Fabio's Pizza
St. Clairsville Center • Classic Hometown Pizzeria • Go-To For Generous Portions
A cozy, no-frills parlor known for hefty pies, plenty of cheese, and small-town hospitality.
Fabio's feels like the kind of place locals grow up with, and it shows in the steady stream of regulars. The pizzas lean hearty, with a chewy crust, bold sauce, and toppings that don’t skimp. It’s an easy choice when you want a satisfying, old-school pie after a short drive down from Lloydsville.
02
Best for specialty pies
DeFelice Bros. Pizza
West Side Of St. Clairsville • Regional Ohio Valley Pizza Shop • Best For Loaded Specialty Pies
A longtime Ohio Valley chain turning out saucy, topping-heavy pizzas with a distinctly local feel.
DeFelice Bros. is a regional staple, and the St. Clairsville location is a convenient option for Lloydsville pizza runs. The menu leans into fully loaded specialty pies, with everything from classic pepperoni to meat-heavy combos that can feed a crowd. Expect a familiar, slightly nostalgic vibe and consistently satisfying takeout or delivery.
03
Best low-key hangout
Papa D's Pizza
Residential Stretch North Of St. Clairsville • Casual Dine-In Pizza Spot • Relaxed Night Out With Friends
A laid-back local shop where the atmosphere is as comfortable as the pizza is dependable.
Papa D's is the kind of place you wander into in sweats and feel right at home. The pizzas are straightforward and satisfying, with a focus on familiar toppings, crispy edges, and shareable sizes. It’s a good pick when you want to sit down for a relaxed meal instead of rushing back to Lloydsville with a box in hand.
04
Best variety beyond pizza
Pizza Milano
Retail Corridor By I-70 • Italian-Style Pizza And Pasta Counter • Best For Variety Beyond Pizza
A versatile stop where you can grab a well-built pizza alongside Italian-style subs and pasta dishes.
Pizza Milano is handy when your group can’t agree on just pizza. The pies are sturdy and flavorful, but the menu also runs through calzones, pasta, and sandwiches, making it easy to please mixed cravings. It’s a smart choice when you’re combining errands near St. Clairsville with a takeout run back to Lloydsville.
05
Most reliable late option
Domino's Pizza
Strip Of Chain Spots Near The Mall • National Delivery And Carryout Chain • Reliable Last-Minute Option
A familiar chain that delivers fast, customizable pizzas when convenience matters most.
When it’s late, the weather’s bad, or you just want something predictable, the St. Clairsville Domino's is hard to beat for sheer convenience. Online ordering and tracking make it simple to time a pickup on your way through or line up delivery toward Lloydsville. The menu covers all the basics, plus extras like bread twists and wings to round out a casual night in.